VETSENSE OTIDERM aids in the removal of dead tissue and embedded debris by causing maximum differential swelling between living and dead areas. This is achieved in two ways: Low pH causes separation of collagen molecules by rupturing the hydrogen bonding. The optimum pH to achieve this effect is between pH2 and pH3. The organic acids react with carboxyl and amino groups in the collagen. The insertion of the organic acid forces the collagen chains apart. In both cases, the devitalised tissues absorb water and swell. Healthy tissues are unaffected because of natural barriers to the organic acids and sufficient buffering capacity to maintain a near neutral pH. For topical application only. General cleansing: Use generously to remove dirt, grit, coagulum etc. The residual solution will promote sloughing of de-vitalised tissues. Otitis External: Use liberally to clean the ear canal. When wax is hard the solution may be left in-situ to soften the wax, allowing easy removal next day. This process can be repeated 2-3 times daily if necessary. Active Constituents: Malic Acid 22.50mg/mL, Benzoic Acid 1.50mg/mL, Salicylic Acid 0.37mg/mL, Propylene Glycol 415.00mg/mL